10 results
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... Summary Mechanisms ... #Pharmacology # ... Summary #DM2 #diabetes
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
PDE5 inhibitors ... #pharmacology #comparison ... #treatment #medications ... #dosing #drugs ... #table #pharmacotherapy
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
anticoagulation in North America ... clearance (calculated using ... interruption per treatment ... table ... #pharmacology #
Summary of Pharmacology for Select Proposed COVID-19 Treatments

#Pharmacology #Dosing #Table #COVID19 #Coronavirus #SARSCOV2 #Medications #JAMA
Summary of Pharmacology ... Proposed COVID-19 Treatments ... #Pharmacology ... #Dosing #Table
NSAID Dosing in CKD
 • Carboxylic Acids: Salsalate, Choline Mg trisalicylate
 • Acetic Acids: Indomethacin, Tolmetin,
NSAID Dosing in ... trisalicylate • Acetic ... Nabumetone • COX-2 Inhibitors ... #CKD #pharmacology ... #table
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
Summary of actions ... Bethanechol • Used in treatment ... Produces miosis during ... Cholinergic #Agonists #Pharmacology ... #Table #Summary
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
Phosphodiesterase-4 (PDE4) Inhibitor ... Eosinophils < 100 Dosing ... : 250 mcg tablet ... recommendations for the treatment ... #Indications #Pharmacology
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Allopurinol Pharmacology ... Summary Xanthine ... oxidase inhibitor ... chemotherapy Dosing ... : 100 mg/m2/dose
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
(folinic acid) treatment ... ineffective because MTX inhibits ... Leucovorin dosing ... , up to 100 mg/m2 ... Toxicity #Management #Pharmacology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
, 350 mg/m2, and ... ) and initiate treatment ... system (RAAS) inhibitor ... every 3 months during ... cardiology #oncology #pharmacology