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AKI in Cirrhosis - Hepatorenal Syndrome Management Algorithm

DOI: 10.1136/bmj.m2687

#AKI #Cirrhosis #Hepatorenal #Syndrome #HRS #Management #Algorithm #nephrology
AKI in Cirrhosis ... - Hepatorenal Syndrome ... bmj.m2687 #AKI #Cirrhosis ... #Hepatorenal #Syndrome
Cirrhosis - Pathophysiology
 - Ascites Formation
 - Dilutional Hyponatremia
 - Hepatorenal Syndrome
 - Spontaneous Infections

#Cirrhosis #Pathophysiology
Cirrhosis - Pathophysiology ... Hyponatremia - Hepatorenal ... Infections #Cirrhosis
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
Pharmacological Treatment of Hepatorenal ... - Long-acting analogue ... - Vasopressin analogue ... 34t5DgJ #HRS #HepatoRenal
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
Liver Disease (Cirrhosis ... Syndrome (HPS) • Hepatorenal ... #ESLD #Liver #Cirrhosis
Hepatorenal Syndrome Treatment
Volume expansion: 
 • Albumin (typical dose = 1g/kg on day 1 +/- day
Hepatorenal Syndrome ... - Somatostatin analogue ... EricsMedicalLectures/ #Hepatorenal
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Hepatorenal Syndrome ... in 3 months • Cirrhosis ... disease - Cirrhosis ... disease - Cirrhosis ... drkeithsiau #HRS #Hepatorenal
Approach to the Hospitalized Patient with Cirrhosis
1) Recognize and Manage Decompensation
 • Ascites
 • Variceal Bleeding
Hospitalized Patient with Cirrhosis ... Alcoholic Hepatitis • Hepatorenal ... DeanEhrlich_MD #inpatient #Cirrhosis
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... antibiotics • Hepatorenal ... Indications #Management #Cirrhosis
Coagulation management in the bleeding cirrhotic
#Management #INR #Coagulopathy #Cirrhosis #Cirrhotic #TEG #Transfusions
in the bleeding cirrhotic ... #Coagulopathy #Cirrhosis ... #Cirrhotic #TEG
Complications of Portal Hypertension
 • Hepatic Encephalopathy
 • Pulmonary: Hepatopulmonary syndrome, Portopulmonary hypertension, Hepatic hydrothorax
 •
hydrothorax • Cirrhotic ... Pancytopenia • Renal: Hepatorenal