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diagnosis hematology deficiency morphology rbc bariatric bloodcell bypass causes cirrhosis cobalamin deficiencies hepatology key management mcv mds microscopy morphologic myelodysplasia
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
anemia • Vitamin ... B12 - Macrocytic ... anemia, cognitive ... - Anemia • Zinc ... cognitive dysfunction, anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
• Microcytic - ... Iron-deficiency ... diseases, Bleeding gastric ... Post-splenectomy, Vitamin ... key #diagnosis #differential
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
E - Haemolytic anaemia ... paraesthesiae • Folate - Anaemia ... B12 - Anaemia, ... #diagnosis #signs ... #symptoms #nutrition
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... MCV - <80fL - "Microcytic ... " • Iron deficiency ... Megaloblastic: Vitamin ... B12 deficiency,
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia ... Chronic disease anemia ... RBC: Vitamin B12 ... RBC #Morphology #differential ... hematology #microscopy #atlas
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... autoantibodies (pernicious anemia ... anemia, yellow ... wt loss • If anemia ... - CBC, PBS - anemia
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia ... B12 deficiency, ... syndrome, Spur cell anemia ... Autoimmune hemolytic anemia ... Kumfer @AnnKumfer #Anemia
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
Etiologies of Vitamin ... • Abnormal gastric ... autoantibodies (pernicious anemia ... VitaminB12 #deficiency #differential ... diagnosis #hematology #nutrition
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... anemia DDX: ... • Aplastic Anemia ... Megaloblastic Anemia ... : vitamin B12 or
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