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diagnosis hematology algorithm causes deficiency elevatedmcv mcv vitamin atlas bariatric bloodcell bypass cobalamin deficiencies fatigue gastric ibd macrocytic mds microscopy
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach to Anemia ... inflammation) • Iron ... Sideroblastic anemia ... ACD, Aplastic anemia ... MatthewHoMD #Anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... • Pernicious Anemia ... • Pernicious Anemia ... #Anemia #Macrocytosis
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... MCV - <80fL - "Microcytic ... " • Iron deficiency ... Megaloblastic: Vitamin B12 ... morphologic #mcv #differential
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Volume (MCV) - Differential ... TlBC > 18% • Anemia ... #Microcytic #Anemia ... #Macrocytosis #
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
anemia • Vitamin ... B12 - Macrocytic ... anemia, cognitive ... - Anemia • Zinc ... cognitive dysfunction, anemia
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia ... Sideroblastic anemia ... RBC: Vitamin B12 ... deficiency anemia ... RBC #Morphology #differential
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
E - Haemolytic anaemia ... paraesthesiae • Folate - Anaemia ... - Anaemia, neurological ... #diagnosis #signs ... #symptoms #nutrition
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Diagnosis and Management ... Summary Clinical Signs ... hypercalcemia) • Anemia ... plus one of: • Anemia ... #oncology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
autoantibodies (pernicious anemia ... anemia, yellow ... wt loss • If anemia ... - CBC, PBS - anemia ... #nutrition
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
, Anemia • Prevalence ... Crohn's > UC Anemia ... If persistent macrocytosis ... Receptor (sTfR) to differentiate ... Algorithm #diagnosis #management
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