11 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Decr Serum K, Mg, Ca ... hemolysis - anemia ... - CNS: Tremors ... #diagnosis #pathophysiology ... #symptoms #signs
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... systemic complaints- anemia ... Treatment of GCA ... #Temporal #Signs
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... - Underlying cancer ... lymphoma, breast CA ... - Hematologic ... Treatment: - Systemic
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... basal ganglia, CNS ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Autoimmune disease, Cancer ... Etiology: • Pathophysiology ... epilepticus Treatment ... underlying cause • Treatment
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Physical Exam/Signs ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... high LDH, low Ca ... interventional radiology ... ) - Symptoms: CNS ... ) - Treatment:
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... develop in pts with GCA ... affects the skin, neurologic ... cognitive impairment, neurologic ... chorioretinitis, CNS
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Unresponsive wakefulness syndrome ... • Locked-in syndrome ... • Mutism Pathophysiology ... • Examine for signs ... #PhysicalExam #neurology