15 results
Causes of Aplastic Anemia

#Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic ... Anemia #Aplastic ... #Anemia #Causes ... #Pathophysiology ... #Pathology #Treatment
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... • Symptomatic anemia ... megaloblastic anemia ... #Anemia #diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... AnemiaAnemia ... Non-lmmune #Anemia ... #Classification ... #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... and petechiae Causes ... anemia Treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... #hematology #oncology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... systemic complaints- anemia ... of the steroid treatment ... Treatment of GCA ... #Signs #Symptoms
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... Chronic hemolytic anemia ... multifactorial mechanisms Hematologic ... disorders Others: tumoral ... #Differential #Causes
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • AnemiaAplastic ... Anemia • Bone ... Megaloblastic Anemia ... Myelophthisic Anemia
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Crises can be precipitated ... The underlying pathophysiology ... ischaemia. 2) Aplasia ... of the baseline anaemia ... Crisis #Features #Signs
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Causes of Neutropenia ... hypertension and/or drug treatment ... Megaloblastic anemia-rare ... white blood cell aplasia ... #hematology