641 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Megaloblastic Anemia ... Autoimmune hemolytic anemia ... Bite cells: G6PD deficiency ... Peripheral #Blood #Smear
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... and severe iron deficiency ... anemia. ... BloodSmear #Blood #Smear
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Normochromic RBCs on Smear ... Reticulocytes • Iron Deficiency ... • B12/Folate Deficiency ... Spherocytes on Smear
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
peripheral blood smear ... changes with iron deficiency ... anemia. ... PeripheralBloodSmear #BloodSmear #Anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Normal Blood Smear ... • Dietary Deficiency ... • Pernicious Anemia ... B12 and Folate Deficiency
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Peripheral blood smear ... DAT (-) → G6PD Deficiency ... → Sickle Cell anemia ... Microangiopathic hemolytic anemia
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
of macrocytic anemia ... ordering a peripheral smear ... elevated, but anemia ... if vitamin B12 deficiency ... occur with B12 deficiency
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... Acute hemolysis, deficiency ... anemia, Rebound
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... • Aplastic Anemia ... or folic acid deficiency ... treatments • Copper deficiency ... Peripheral blood smear
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Abnormal peripheral smear ... Autoimmune Hemolytic Anemias ... #Hemolytic #Anemias