39 results
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... Fanconi Anemia ... Anemia Dyskeratosis ... #anemia #diagnosis ... #Hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Neutropenia with Pancytopenia ... - Differential ... • Toxins • Aplastic ... Anemia • Myelodysplasia ... #Neutropenia #Differential
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Deficiency • Aplastic ... AnemiaAnemia ... Non-lmmune #Anemia ... #Classification
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Workup #Differential ... Diagnosis #Algorithm #Hematology
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Abnormal peripheral smear ... Autoimmune Hemolytic Anemias ... #Hemolytic #Anemias
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Workup #Differential ... Diagnosis #Algorithm #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... Diagnosis: • Pancytopenia ... megaloblastic anemia ... #Anemia #diagnosis
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Testing in Hemolytic Anemia ... LDH Peripheral smear ... #Hemolytic #Anemia ... Laboratory #Testing #workup ... #diagnosis #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... as in Fanconi anemia ... anemia) Labs
Algorithm for the Diagnosis and Workup of Hemolytic Anemia

By Dr. Kylie Adamek @KylieAdamek

#Hemolytic #Anemia #Algorithm #Differential
Diagnosis and Workup ... of Hemolytic Anemia ... #Hemolytic #Anemia ... #Algorithm #Differential ... #Hematology #Hemolysis