32 results
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential ... Diagnosis Framework ... nodules, Deep ulcers ... #dermatology #rheumatology ... diagnosis
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
thickening Signs and Symptoms ... Raynaud's, digital ulcers ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... meningitis), MCC CNS symptoms ... Behcet disease) Differential ... #management #signs ... #symptoms #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... organ-specific signs or symptoms ... (eg, skin or esophageal ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Anterior ischemic ... thrombosis of short ... • Cephalic symptoms ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Nephropathy 16% - Oral ulcers ... (aPL) 30-45% Differential ... autoantibodies #signs #symptoms ... #mimickers #differential ... #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... fraction < 20% Differential ... Diaqnoses: • ... #management #treatment ... #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... sensitivity • Painful ulcers ... Cryofibrinogenemia Diagnosis ... #rheumatology # ... hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Associated with skin ... Hydroxychloroquine *Short ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Symptoms: • The ... Criteria for Diagnosis ... Skin involvement ... Resolution > 15 days Differentials ... #diagnosis #management