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diagnosis algorithm causes hematology bruising erythematosus sle systemic autoantibodies bleeding classification dermatology glomerulonephritis hemostasis mimickers monoclonal oncology paraproteinemias pediatrics peds
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Neurological 12% - Thrombocytopenia ... (aPL) 30-45% Differential ... Diagnosis and Lupus ... symptoms #mimickers #differential ... #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential ... Diagnosis Algorithm ... Alloimmune • anti-HLA ... HUS • DIC • Vasculitis ... #Causes #Hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
(anti-C1q Vasculitis ... such as systemic lupus ... testes -> pain, infarct ... differential #diagnosis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Non-autoimmune rheumatologic ... Erythematosus #Diagnosis ... #Rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Diagnosis Algorithm ... hemostasis: - Thrombocytopenia ... (lupus, RA, Sjogren's ... electrophoresis, anti-streptolysin
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
SLE (systemic lupus ... infections - Vasculitis ... Bruising #Causes #peds ... #pediatrics #diagnosis ... #differential #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
nemaline myopathy • Anti ... Autoimmunity: • -MM/WM: Vasculitis ... to cold IgG • Lupus ... #Monoclonal #Differential ... #Diagnosis #Oncology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... Diagnosis Framework ... inhibitor and lupus ... integrity == • Vasculitis ... #Diagnosis #Hematology
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