866 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
activity Anti-Ro ... block • Sjogren syndrome ... polymyositis overlap syndrome ... ) Anti-Smith - ... Treatment: •
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... SLE • Mikulicz syndrome ... • Antibodies: Anti-Ro ... /SSA & Anti-La/SSB ... Adenocarcinoma Treatment
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
: • Anti-GAD Ab ... poisoning, Parkinson's disease ... Treatment: • ... Baclofen • Severe Disease ... Diagnosis #Management #treatment
Celiac disease is an immune-mediated, multisystem disorder that affects genetically susceptible individuals who are exposed to
mainly Sjogren’s syndrome ... and William’s syndromes ... antibodies measured are anti-tissue ... numerically) and anti-endomysial ... is the primary treatment
Staphylococcal Scalded Skin Syndrome (SSSS) 
(aka Ritter disease) 
Nikolsky positive 
Clinical 
• Typically occurs 3 to
Staphylococcal Scalded Skin Syndrome ... (aka Ritter disease ... oxacillin (or any anti-staphylococcal ... CA-MRSA or initial treatment ... Scalded #Skin #Syndrome
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... Pulmonary Renal Syndromes ... life-threatening diseases ... Inflammatory eye disease ... diagnosis #management #treatment
Treatment Options for Helicobacter Pylori and Peptic Ulcer Disease

Active Helicobacter pylori—associated ulcer
1. Treat with anti—H pylori
Treatment Options ... and Peptic Ulcer Disease ... Treat with anti—H ... Treatment options ... Zollinger-EIIison syndrome
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... ' disease c-ANCA ... syndrome #Autoantibodies
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Pulmonary Renal Syndromes ... Goodpasture's Disease ... testing: anti-ANCA ... ab, anti-GBM ab
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... Nephritic syndrome ... glomerulonephritis - Berger disease ... Minimal change disease ... #Glomerular #Diseases