1469 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Mediators: lgE - Antigen ... Form: Soluble antigen ... Acute transfusion reaction ... hypersensitivity #reactions
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... syndrome, POEMS • Reaction ... Exercise, Allergic reactions ... Diagnosis #Algorithm #hematology
Algorithm for the Evaluation and Management of Transfusion Reactions

This algorithm was developed by Dr. Eric Madden,
of Transfusion Reactions ... #Transfusion #Reactions ... Diagnosis #Management #Hematology
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Penicillin-induced drug reaction ... Immunological Target: Antigen-Ab ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Sensitization -> Antigen ... class II) process antigen ... Primary Reaction ... Secondary Reaction ... after the primary reaction
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Cutaneous Drug Reactions ... IgE-mediated reactions ... T-cell-mediated reactions ... T-cell-mediated reactions ... #dermatology #clinical
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
during an allergic reaction ... Or Inflammatory Reactions ... Diagnosis #causes #hematology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Drug Reaction with ... hypersensitivity reaction ... with allergic reaction ... Images #Clinical #Dermatology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Drug Reaction with ... hypersensitivity reaction ... with allergic reaction ... Images #Clinical #Dermatology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
lgE - Soluble antigen ... IgM - Cell-bound antigen ... IgM - Soluble antigen ... - Antigen-antibody ... Allergy #Diagnosis #Reactions