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Lupus Nephritis Classification Algorithm

#Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... #Classification ... Algorithm #diagnosis #differential ... #types #rheumatology ... #nephrology #renal
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Renal #diseases #SLE ... Erythematosus #venn #nephrology ... #nephritis #classification ... #types #rheumatology
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... DrFlashHeart #Lupus #Nephritis ... #SLE #Classification ... #Classes #differential ... diagnosis #management #nephrology
Nephrotic Syndrome - Classification
 - Podocytopathies
 - Immunocomplex Deposits 
 - Other substances Deposits 

#Nephrotic #Syndrome
Nephrotic Syndrome ... - Classification ... Deposits #Nephrotic ... #Differential # ... Diagnosis #Nephrology
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the Treatment ... treat non-renal SLE ... treat extra-renal SLE ... #Algorithm #Treatment ... #management #nephrology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... by 12 months Classification ... #Management #treatment ... #management #rheumatology ... #nephrology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... least 2 joints • Neurologic ... II or V lupus nephritis ... Ill or IV lupus nephritis ... #Criteria #SLE
Intrinsic Renal Disease - Differential Diagnosis
Vascular:
 • Macrovascular: Renal artery occlusion, Fibromuscular disease
 • Microvascular: TTP/HUS,
Renal Disease - Differential ... Glomerular: • Nephrotic ... toxin-induced: Antibiotics ... Renal #Disease #nephrology ... #differential #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... ulcers, Lupus nephritis ... are evocative of SLE ... life-threatening • Treatment ... Management #Summary #rheumatology