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Nomenclature of Monoclonal Antibodies (-mab)

- Dr. Axel Grothey
@agrothey

#Nomenclature #Monoclonal #Antibodies #Mab #Antibody #Naming
of Monoclonal Antibodies ... Nomenclature #Monoclonal #Antibodies ... #Mab #Antibody
Estimated Timeline for Detection of SARS-CoV-2 Infection Relative to Symptom Onset

#COVID19 #SARSCOV2 #PCR #Serology #Antibodies #Antibody
PCR #Serology #Antibodies ... #Antibody #Laboratory
COVID-19 PCR and Serology Testing - Timeline
 • Nucleic Acid Test - Most reliable and can
first 7 days • Antibody ... PCR #Serology #antibody ... #antibodies #testing
Important Cardiac Transplant Medications and Side Effects
 • Cyclosporine (Sandimmune, generic) - Calcineurin inhibitor, decreasing T
• Polyclonal antibodies ... Antilymphocyte antibody ... • Monoclonal antibodies ... , IL2-receptor antibody ... Antilymphocyte antibody
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear Antibody ... Antineutrophil cytoplasmic antibodies ... anti-topoisomerase antibody ... #Antinuclear #Antibody ... Antineutrophil #antibodies
Hashitoxicosis - Autoimmune thyroid disease overlap syndrome of Graves' and Hashimoto's disease

Autoimmune thyroid disease overlap syndrome
destruction by cell and antibody-mediated ... peroxidase (TPO) antibodies ... immunoglobulin (TSI) antibodies ... • TSH-receptor antibodies ... your balance of antibodies
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Pathogenesis and clinical ... a maladaptive antibody-mediated ... specific pre-formed antibodies ... produce autoimmune antibodies ... entire complex -> Antibody
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
transglutaminase (tTG) IgA antibodies ... antiendomysial antibodies ... results for tTG antibodies ... anti-transglutaminase antibody ... gliadin peptide antibodies
4T Score for Heparin-Induced Thrombocytopenia

Interpretation of the 4T score:
0-3 points:  Low probability (<<1%)
  -
checking heparin-PF4 antibodies ... check anti-PF4 antibody ... check anti-PF4 antibody
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Erythematosus Clinical ... Antiphospholipid antibody ... Highly specific antibodies ... domain: Anti-dsDNA antibody ... , Anti-Sm antibody