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management differential rheumatology hematology neurology workup causes signs algorithm dermatology infectiousdiseases pathophysiology symptoms classification erythematosus lupus syndromes systemic table antinuclear
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
La) - Sjogren's syndrome ... polyangiitis U1-RNP antibody ... Endomyseal antibody ... #diagnosis #table ... #rheumatology #antibodies
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... Antineutrophil cytoplasmic antibodies ... cases • Sjögren syndrome ... Jcortesizaguirr #ANA ... #antibodies #diagnosis
Hashitoxicosis - Autoimmune thyroid disease overlap syndrome of Graves' and Hashimoto's disease Autoimmune thyroid disease overlap syndrome
overlap syndrome ... overlap syndrome ... antibody-mediated ... • TSH-receptor antibodies ... Pathophysiology #Diagnosis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
less common diseases ... important, as early diagnosis ... and treatment can ... encephalomyelitis • MOG antibody-associated ... #differential #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antibody refers ... likely it will be clinically ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #rheumatology #diagnosis
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
LC deposition disease ... Minimal change disease ... malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential #Diagnosis
Commonly Used Diagnostic Tests for Celiac Disease Tissue transglutaminase (tTG) IgA antibodies - Most reliable noninvasive test
Commonly Used Diagnostic ... Tests for Celiac Disease ... anti-transglutaminase antibody ... Reflects response to treatment ... Laboratory #Tests #Diagnosis
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
50 years in men Diagnosis ... : • Based on clinical ... myasthenia usually • Starts ... - Improves clinical ... within 3 years of diagnosis
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... at least: • 1 clinical ... presence of 1 clinical ... to be present Treatment ... Antiphospholipid #Syndrome
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
quantify renal injury ... EGPA) • Auto-antibodies ... : ANCA antibody, ... Anti-GBM antibody ... #management #treatment
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