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diagnosis differential oncology disorders hyperpigmentation mds myelodysplastic skin apml breakthrough cvid differentiation dvt essential et hypogammaglobulinemia hypopigmentation immunodeficiency immunology myelodysplasia
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
Subtherapeutic Anticoagulation ... Structural - Pelvic masses ... - May-Thurner syndrome ... #hematology #differential ... #algorithm
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... • Risks: infection ... Myelodysplastic #Syndrome ... #treatment #hematology
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm HYPOPIGMENTATION Diffuse Congenital - Generalized hypopigmentation of
Differential Diagnosis Algorithm ... McCune Albright syndrome ... versicolor (more commonly ... disorders #skin #dermatology ... #causes
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Attempt if high risk ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
increased infection risk ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... Most common cytopenia ... (CML) • Felty Syndrome ... #diagnosis #hematology
Skin Hyperpigmentation - Differential Diagnosis Algorithm Diffuse: • Tanning • Adverse cutaneous drug eruption • Addison's disease
Differential Diagnosis Algorithm ... McCune Albright syndrome ... versicolor (more commonly ... disorders #skin #dermatology ... #causes
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
• Treatment algorithms ... Hydroxyurea + anticoagulation ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
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