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differential leukemia treatment anemia chronic cll lymphocytic mds monoclonal myelodysplastic acquired algorithm aplastic behcet blood classification common cryofibrinogenemia cvid dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Metastatic cancer, Lymphoma ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management ... old, ~10,000 new cases ... Myelodysplastic #Syndrome ... #hematology #oncology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
- Diagnosis and ... disorders (e.g. lymphoma ... thrombocythemia), Autoimmune disease ... #Diagnosis #Management ... #treatment #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... e.g. lupus, CLL, lymphoma ... , Copper and lead ... #hematology #anemia
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Myeloproliferative disease ... • Nephrotic Syndrome ... other causes of ... pathophysiology #hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Causes of false- ... Other causes of ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Lymphoma or ... • Nodules • Lymphoid ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
lymph node biopsy (diagnostic ... number of sites of disease ... #diagnosis #classification ... #hematology #oncology ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... cells can indicate disease ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulins • Negative causes ... to medium-sized arteries ... Antiphospholipid syndrome ... #rheumatology # ... hematology
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