24 results
ACEi/ARBs in COVID-19: Beneficial, Bad, or Benign?
Preclinical studies suggest ACEi/ARB use increases ACE2 expression, raising concern
ACEi/ARBs in COVID ... Beneficial, Bad, or Benign ... David Rink, MS4 ... Kerryn Roome, MS4 ... #Coronavirus #Pathophysiology
Apley Compression Test on Knee Examination

With the patient prone, the knee being tested is flexed to
Apley Compression ... prone, the knee being ... along with the Apley ... PT_yuu_mizu628 #Apley ... #orthopedics #msk
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Hyperkalemia • Direct renin ... Aliskiren) • Renin ... Angiotensin-converting enzyme (ACE ... #hyperkalemia #differential ... #diagnosis #pathophysiology
Jaundice - Pathophysiology and Causes

- Amy Chung, MD, MSc @AmyChung 

#Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... Amy Chung, MD, MSc ... #Jaundice #Pathophysiology ... #Differential #
Etiologies of Hypoaldosteronism

Hyporeninemic Hypoaldosteronism (Low Renin, Low Aldosterone)
 - Diabetic Nephropathy 
 - NSAIDs
Non-Hyporeninemic Hypoaldosteronism (Normal
Normal or High Renin ... Aldosterone) - ACE ... Normal or High Renin ... Hypoaldosteronism #Differential ... #Diagnosis #Renin
Renin-Angiotensin-Aldosterone System (RAAS) 

The kidneys produce renin in response to low blood pressure or low plasma
Renin-Angiotensin-Aldosterone ... kidneys produce renin ... Renin acts on angiotensin ... angiotensin-converting enzyme (ACE ... #Pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... ARBs Decreased Renin ... #Hyperkalemia #Pathophysiology
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
- SLE High Renin ... LMW heparin - ACE-I ... Ketoconazole Low Renin ... Algorithm #diagnosis #differential
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
Bone Tumors - Differential ... Renal Primary Benign ... Tumors #Tumours #MSK ... #Differential #
Increased Urinary Frequency - Differential Diagnosis Algorithm
Non-increased urine volume (<2mL/min), Rule out polyuria
Extrinsic to Urinary Tract:
Urinary Frequency - Differential ... Obstruction: • Benign ... • Diabetes • MS ... Urinary #Frequency #Differential