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diagnosis algorithm hypokalemia low high management pharmacology binders binding chronic ckd comparison druginduced encephalopathy kidneydisease neurology pathophysiology posterior pres reversible
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ; constipation, ... , constipation, ... of aspiration #Potassium ... #medications #pharmacology
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... - Differential ... renovascular HT, Renin-secreting ... #differential # ... #nephrology #potassium
Constipation - Differential Diagnosis Algorithm Diet/Lifestyle • Fibre • Calories • Fluid • Exercise • Psychosocial Medications •
Constipation - Differential ... Aluminum, Calcium, Potassium ... • Hypercalcemia ... #Differential # ... Diagnosis #Algorithm #Causes
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... wasting from other causes ... suggests extra-renal causes ... diagnosis #Algorithm #differential ... #potassium #nephrology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... Increased EC shift of K ... #differential # ... #pharmacology #potassium ... #medications #druginduced
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Medications 2. ... #differential # ... diagnosis #causes ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Hypokalemia - Differential ... Thyrotoxicosis Medications ... vomiting) • Low K ... Diagnosis #Algorithm #nephrology ... #low #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Medications 2. ... #differential # ... diagnosis #causes ... #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... syndrome #hypokalemia ... #urine #potassium ... #differential # ... algorithm #diagnosis #nephrology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Renovascular HTN, Renin ... Diagnosis #Algorithm #causes ... #potassium #low ... #nephrology
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