27 results
diagnosis differential algorithm causes dermatology hemolytic management rheumatology secondary workup aflp comparison generalized hellp hepatology infectiousdiseases obstetrics oncology pregnancy pruritus
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... breakdown • Anaemia ... #Hemolytic #Anemia ... Causes #Workup #Hematology ... GrepMed Recommended Text
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
syndrome (ST-HUS ... anemia" • HELLP ... syndrome • Catastrophic ... differential #diagnosis #hematology ... #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... ) - HELLP syndrome ... uremic syndrome ... differential #diagnosis #hematology ... #anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... uremic syndrome ... #differential #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... Laboratory Tests ... Differential #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... anemia • Cold ... • Diagnostic Test ... Donath-Landsteiner test ... #anemia #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis ... Differential #Diagnosis #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
value is low, tests ... result in severe anemia ... indirect antiglobulin tests ... anemia Indirect ... Diagnosis #Workup #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... iron deficiency, hemolysis ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... blood loss, Acute hemolysis ... , deficiency anemia ... Kawasaki, Nephrotic syndrome
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