13 results
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
: • Recurrent infections ... Treatment: • Consider ... (transfusions, antibiotics ... #diagnosis #management ... #treatment #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... ) - Drugs ( ... Beta lactam antibiotics ... #anemia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- Cytotoxic drugs ... - β-lactam antibiotics ... Idiopathic • Infections ... Treatment: ... #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... only curative treatment ... #treatment #hematology
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
Allergy Pathway for Antibiotic ... Stevens-Johnson syndrome ... interstitial nephritis, Drug ... , Hemolytic anemia ... Prescription #algorithm #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... isoniazid) • Antibiotics ... • Parvovirus infection ... factor (GCSF) treatments ... #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : • Infection ... rapidly, and empiric antibiotic ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
treatment - Maternal ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... Megaloblastic anemia-rare ... diagnosis #causes #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
SLE], AOSD) • Infection ... ) • Sepsis • Drug-induced ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Diagnosis #Management
Treatment Options for Helicobacter Pylori and Peptic Ulcer Disease

Active Helicobacter pylori—associated ulcer
1. Treat with anti—H pylori
Treatment Options ... completion of antibiotic ... Zollinger-EIIison syndrome ... the preferred drugs ... #Management #Pharmacology