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symptoms differential sle erythematosus nephrology syndrome systemic classification arthritis behcet crisis criteria cryoglobulinemia cryoglobulinemic disease druginduced eularacr gca giantcell hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... such as systemic lupus ... purpura: strong sign ... • Urinalysis (Renal ... #rheumatology #
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Complex: Systemic lupus ... erythematosus, Rheumatoid arthritis ... #differential #diagnosis ... #nephrology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
• Arthritis domain ... least 2 joints • Neurologic ... hemolysis • Renal ... Erythematosus #diagnosis ... #rheumatology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
Renal involvement ... cryoglobulinemia vasculitis ... TerrierBen #Renal ... #Management #Rheumatology ... Cryoglobulinemic #Nephrology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... skin injury) • Neurologic ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... Erythematosus #Diagnosis ... #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... pulmonary and renal ... purpura: Strong sign ... affects the skin, neurologic ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Usual therapeutic management ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... = vasculitis vs ... them, but urgent rheumatology ... #Management
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