18 results
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
in Autoimmune Hemolysis ... DAT Negative Hemolysis ... , C3d ( +/- ) Paroxysmal ... #antiglobulin #test ... #hematology #diagnosis
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
abnormal liver tests ... Pattern #LFTs #transaminits ... obgyn #obstetrics #hepatology ... #diagnosis #differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... Transfusion reaction, Paroxysmal ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... #Hemolytic #Anemia ... #Algorithm #Differential ... Causes #Workup #Hematology ... GrepMed Recommended Text
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - Differential ... Donath-Landsteiner HA (paroxysmal ... #Autoimmune #Hemolytic ... Diagnosis #Table #hematology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Liver Function Tests ... (LFTs) - Differential ... #LFTs #Differential ... #Diagnosis #hepatology ... #transaminitis
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... erythematosus • HLH • Paroxysmal ... Antibody-mediated hemolysis ... #Pancytopenia #Differential ... #Diagnosis #Hematology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... ) vs Indirect (Hemolytic ... LFTs #Elevation #Transaminitis ... #diagnosis #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
2-5x normal - Hemolysis ... Liver #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Liver Function Tests ... - Differential ... Algorithm for Transaminitis ... Elevated #Abnormal #Transaminitis ... Algorithm #diagnosis #hepatology