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diagnosis hematology anemia algorithm hemolytic causes hepatitis injury liver agglutinin aiha antiglobulin atlas bloodcell classification cold dat direct disease extravascular
Anemia - Hemolysis Diagnostic Algorithm Autoimmune hemolytic anemia Microangiopathic hemolytic anemia Probable thalassemia Dr. Eric Strong @DrEricStrong - Strong Medicine
Anemia - Hemolysis ... Diagnostic Algorithm Autoimmune ... Anemia #Algorithm #hematology ... #diagnosis #differential ... #workup
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
DAT Results in Autoimmune ... , C3d ( +/- ) Paroxysmal ... #antiglobulin #test ... #DAT #Autoimmune ... #Hemolysis #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - Differential ... Donath-Landsteiner HA (paroxysmal ... #Hemolytic #Anemia ... Diagnosis #Table #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Transfusion reaction, Paroxysmal ... Immune-mediated: - Autoimmune ... idiopathic) - Autoimmune ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis ... GrepMed Recommended Text
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... Inflammatory and Autoimmune ... erythematosus • HLH • Paroxysmal ... Antibody-mediated hemolysis ... #Diagnosis #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... elliptocytosis, autoimmune ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Membrane): - Autoimmune ... Laboratory Tests ... #Differential # ... Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... younger pts) Differential ... macroglobulinemia Paroxysmal ... • Diagnostic Test ... #anemia #hematology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Liver Injury - Differential ... Injury → liver test ... Other: NAFLD, Autoimmune ... #Diagnosis #hepatology ... #algorithm #Transaminitis
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