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diagnosis hematology causes management abnormal acidosis activation agglutinin aplastic cancer chronic classification cll cold disease dyspnea elevatedmcv elevation enzymes hemolysis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Myelodysplastic Syndromes ... Liver Function Tests ... #Causes #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... Laboratory Tests ... Haptoglobin ↓ - Lactate
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
algorithm. ... presence of metabolic syndrome ... normalised ratio; LDH, lactate ... #Hepatology #Liver ... #Enzymes #Differential
Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion
metastases Treatment ... - Cytopenias (anemia ... Changes in Pre-Test ... #differential # ... diagnosis #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... propylthiouracil) - β-lactam ... Treatment: ... #oncology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... or diagnostic tests ... before beginning treatment ... - Compartment syndrome ... 30mmHg) - Severe anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... • Diagnostic Test ... Donath-Landsteiner test
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
with leukopenia, anemia ... Liver function tests ... Triglycerides • ↑ Lactate ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
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