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hematology treatment lupus sle adultonset causes classification coagulation common comparison cvid dic differential disseminated druginduced erythematosus fungal hodgkins hypogammaglobulinemia immunodeficiency
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Differential Diaqnoses ... CK, normal biopsy ... #diagnosis #management ... #treatment #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... - CRP: Usually normal ... Evolution: Chronic disease ... #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... to 8 years Clinical ... and M panel Management ... levels are within normal ... #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... • Severe Liver Disease ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Pheochromocytoma - Diagnosis and Management Summary 10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
Pheochromocytoma - Diagnosis ... bilateral, malignant, pediatric ... hypertension; some normal ... hypotension (may reflect ... Treatment • Operable disease
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
and Management ... CLINICAL: • Physical ... based on clinical ... generally are normal ... #Management #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Spasticity - Reflexes ... bouts of HTN Diagnostic ... Sjogren's • CSF: - Abnormal ... #management #neurology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... lymph node biopsy (diagnostic ... number of sites of disease ... Hodgkins #lymphoma #diagnosis ... #oncology #management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... has five major clinical ... fungal stain of clinical ... level • A low or normal ... #Management #Infections
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