14 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Diagnosis and Management ... lesions (a), Brain: normal ... Neuritis #Diagnosis #Management ... #treatment #rheumatology ... #ophthalmology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal ... causes #treatment #management ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... CSF PROTEIN - NORMAL ... Syndrome #diagnosis #management ... #treatment #neurology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Person Syndrome Pathophysiology ... Oligoclonal bands • Normal ... SPS #Diagnosis #Management ... #treatment #neurology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
50 in GCA, but normal ... them, but urgent rheumatology ... required +/- prompt ophthalmology ... Symptoms #Diagnosis #Management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
protein with a normal ... - Of note, normal ... the underlying pathophysiology ... Syndrome #diagnosis #management ... #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Sjogren's • CSF: - Abnormal ... Myelitis #diagnosis #management ... #neurology #differential
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
hypertension 3) Abnormal ... anemia (MAHA) Pathophysiology ... Renal #Crisis #rheumatology ... #nephrology #diagnosis ... #management