13 results
diagnosis rheumatology treatment barre differential guillain nephrology apml behcet causes cerebritis coagulation crisis dic differentiation disease disseminated erythematosus fungal gbs
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... #neurology #rheumatology ... cerebritis #diagnosis #management
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... Metabolic alkalosis • Normal ... #nephrology #management ... #pathophysiology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... #diagnosis #management ... signs #symptoms #rheumatology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... CSF PROTEIN - NORMAL ... #diagnosis #management ... #treatment #neurology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... - APTT < 1.5 x normal ... causes #treatment #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Pathophysiology ... Oligoclonal bands • Normal ... SPS #Diagnosis #Management ... #treatment #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... Guillain #Barre #Syndrome ... #diagnosis #management ... #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
affects the skin, neurologic ... cognitive impairment, neurologic ... fluid (CSF) is abnormal ... chorioretinitis, CNS ... vasculitis • Cogan syndrome
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... Sjogren's • CSF: - Abnormal ... Myelitis #diagnosis #management ... #neurology #differential
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