28 results
Prehension / Adult Palmar Grasp Reflex (Abnormal)
Notice friends that the patient always "tries to grab" my
(Abnormal) Notice ... like something "normal ... can be present normally ... #Adult #Neurology ... clinical #video #abnormal
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... etiology of coma Abnormal ... movements; also normal ... flexion withdrawal, abnormal ... decortication), abnormal
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview Normal ... Segmented Neutrophil (Normal ... shock, 33% had normal ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... Diagnosis and Management ... hemosiderin • PT/aPTT normal ... #Diagnosis #Management ... #Algorithm #hematology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Idiopathic • Normal ... Glomerulonephritis #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... • Muscular: normal ... CK, normal biopsy ... Disease #diagnosis #management ... #treatment #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Thrombocytopenia - Abnormal ... deficiency - Abnormal ... blood test • Serology ... Petechiae #Rash #Differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... • ALT & AST normal ... • Bilirubin - Normal ... bile ducts Differential ... diagnosis #workup #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... Decreased / Absent Reflexes ... CSF PROTEIN - NORMAL ... Syndrome #diagnosis #management ... #treatment #neurology