5 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • ... high WBC count cause ... fever - ACS, AKI ... , acute limb ischemia ... hydration - Hyperkalemia
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Distributive Shock, HRS, Hypercalcemia ... ANCA, Anti-GBM, C3 ... Diagnosis #nephrology #causes ... #algorithm
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
- AKI Workup Algorithm ... osmolarity If cause ... , Anti-ds-DNA, C3 ... #Workup #Algorithm ... Diagnosis #nephrology #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... Acidosis, Cell Lysis ... , RTA Type IV, AI ... reabsorption) Workup ... only if no clear cause
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... TLS (tumor-lysis ... Treat underlying cause ... anticoagulation Leukostasis ... plasmapheresis Hypercalcemia