34 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... APTT Step 1: Is ... the PT or APTT ... to identify the cause ... ISNeducation #Abnormal
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... Prolonged PT (INR), Normal ... PTT, Normal PT ... , Normal PT (INR ... Diagnosis #Algorithm #Causes
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... Pre-analytical cause ... Jcortesizaguirr #Abnormal ... #Causes #diagnosis
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... Causes include : ... Pre-analytical cause ... amyloidosis #Abnormal
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia - Normal ... Treat primary cause ... INR < 2.3 - APTT ... < 1.5 x normal ... Coagulation #diagnosis #causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... discern these causes
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... may be normal in ... mild cases) • ... antigen (vWF:Ag) are normal
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Proximal Weakness, Normal ... Myopathy (Also caused ... hydroxychloroquine therapy), Normal ... Erythematosus #SLE #MSK
Posterior Ankle Impingement (Os Trigonum) Syndrome - MSK Radiology
Imaging Findings:
 • Os trigonum which has marrow
Trigonum) Syndrome - MSK ... Case description ... , os trigonum, abnormal ... thickening and abnormal ... Radiology #diagnosis #msk
Focal Periphyseal Edema (FOPE lesion) - MSK Radiology
Imaging Findings:
 • Arrows identifying the characteristic edema-like signal
FOPE lesion) - MSK ... This abnormal signal ... Case description ... in these cases ... Radiology #diagnosis #msk