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diagnosis liver aclf algorithm apml causes chronic cirrhosis differentiation dili drug dysphagia failure gravis hematology idiosyncratic injury myasthenia myoclonus oncology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Idiosyncratic #differential ... #gastroenterology ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Hepatitis (AAH) Drug-Induced ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
endothelial damage • Induce ... • Rare: DAH, acute ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Dysphagia - Differential Diagnosis Framework Symptom | Diagnosis • Solid-food dysphagia present for months to years | Mechanical
• Muscular or neurologic ... Other - ALS, Dementia ... weight loss or acute ... #Diagnosis #Management ... #gastroenterology
Causes of Myoclonus - Differential Diagnosis LOCALIZATION: • Cortical: Focal/multifocal: Distal UL+ Face, Action/sensitive induced • Sub-Cortical:
of Myoclonus - Differential ... Action/sensitive induced ... Startle/Auditory induced ... degenerations, dementias ... Diagnosis #Causes #neurology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... Penicillamine induced ... aspiration and acute ... Gravis #diagnosis #management ... #neurology
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