28 results
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Primary Syphilis ... - Ocular syphilis ... and nephrotic syndrome ... impairments, and dementia ... Latent #Tertiary #Diagnosis
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
disorders (MNCD): Diagnosis ... 1) Clinical diagnosis ... hydrocephalus, HIV, syphilis ... functions - Aphaso-apraxo-agnosia ... syndrome - Hippocampal
Natural History of Syphilis
Primary - 2-6 weeks after infection
 • Chancre, Regional lymphadenopathy
Early Latent ≤ 1
Natural History of Syphilis ... Primary - 2-6 weeks ... 2 months after primary ... (10%); Ocular syphilis ... #progression #diagnosis
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Treatment 1) Primary ... Albuminuria, nephrotic syndrome ... Headache, meningitis, ocular ... 30 years after primary ... #stages #diagnosis
Genital Skin Ulcers - Differential Diagnosis Algorithm
Painful:
 • Herpes simplex
 • Haemophilus ducreyi (chancroid)
 • Behcet's
- Differential Diagnosis ... ) • Behcet's syndrome ... Painless: • Primary ... syphilis (chancre ... #Differential #Diagnosis
Causes of Encephalopathy - Differential Diagnosis Algorithm
Hyperacute:
 - Primary Neurologic: Vascular (IS, ICH), Seizure, Migraine, Trauma
- Differential Diagnosis ... Hyperacute: - Primary ... paraneoplastic syndromes ... NPH, Infectious (syphilis ... #Differential #Diagnosis
Genital Lesions - Differential Diagnosis Algorithm
Elevated - Vesicles:
 • Herpes simplex
Elevated - Papules / Plaques -
- Differential Diagnosis ... • Secondary Syphilis ... ) • Reiter's syndrome ... - Painless • Primary ... syphilis (chancre
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
- Differential Diagnosis ... • Aphasia • Apraxia ... Cognition/Confusion, Dementia ... Brown-Sequard Syndrome ... #Differential #Diagnosis
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Stages of Syphilis ... Early Primary: ... • Gummatous • Nodular ... BostonChiefs #Syphilis ... symptoms #signs #diagnosis
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... incontinence, apraxia ... AlzheimersDisease #Dementia ... pathophysiology #geriatrics #diagnosis