9 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... incontinence, apraxia ... aggression #AlzheimersDisease ... #Dementia #pathophysiology ... #geriatrics #diagnosis
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
neurocognitive disorders ... hydrocephalus, HIV ... functions - Aphaso-apraxo-agnosia ... syndrome - Hippocampal ... hallucinations - Movement disorders
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
- Differential Diagnosis ... • Apraxia • ... Cognition/Confusion, Dementia ... Brown-Sequard Syndrome ... #Hemiplegia #Neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... Diagnosis: MRI ... The clinical syndrome ... #dementia #AIDS ... #Neurology
Localizing Extraocular Movement Disorders
 • CN Ill (Oculomotor) Nerve Palsy 
 • CN IV (Trochlear) Nerve
Nerve Palsy • CN IV ... One-and-a-half Syndrome ... ophthalmology #neurology ... #differential #diagnosis ... #ocular
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... - Differential Diagnosis ... , HIV, CMV, HTLV ... MCTD, Sjogren syndrome ... #diagnosis #neurology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Zone Lymphoma (HCV ... et diutinum Neurologic ... predominance) • CANOMAD (Ataxia ... Hypergammaglobulinemic macular ... #Differential #Diagnosis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... impairment, Mood disorder ... Cramping, Weakness, Ataxia ... • Acute: - IV ... #management #neurology
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
Cataracts - Macular ... Examples: - Dementia ... sclerosis • Clues: Ataxia ... Recurrent #Falls #Diagnosis ... Evaluation #Geriatrics #Neurology