45 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... incontinence, apraxia ... AlzheimersDisease #Dementia ... geriatrics #diagnosis #signs
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
functions - Aphaso-apraxo-agnosia ... syndrome - Hippocampal ... atrophy Lewy body dementia ... (parkinsonian signs ... Frontotemporal dementia
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Manifestations of Serotonin Syndrome ... Ophthalmologic: Mydriasis, Ocular ... Diaphresis, flushing • CNS ... Cardiovascular and vital sign ... Symptoms #spectrum #signs
Ocular Apraxia on Physical Exam

Ocular Apraxia is the loss of voluntary and purposeful eye movement while
Ocular Apraxia on ... Apraxia is the ... #Ocular #Apraxia ... PhysicalExam #clinical #video ... #neurology #ophthalmology
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
• Aphasia • Apraxia ... Cognition/Confusion, Dementia ... Brown-Sequard Syndrome ... #Hemiplegia #Neurology
Localizing Extraocular Movement Disorders
 • CN Ill (Oculomotor) Nerve Palsy 
 • CN IV (Trochlear) Nerve
Nerve Palsy • CN ... Nerve palsy • CN ... One-and-a-half Syndrome ... ophthalmology #neurology ... differential #diagnosis #ocular
Iridodonesis

Physical examination revealed iridodonesis, or “dancing” of the iris, which was elicited by rapid movement of
movement, is a sign ... characteristic sign ... with Marfan’s syndrome ... #PhysicalExam #Video ... #Ocular
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... Other brainstem syndromes ... pain • Extra-CNS ... Manifestations #diagnosis #neurology ... #symptoms #signs
Episodic eyelid opening apraxia (without compensatory brow lift) and forced downgaze due to transient shunt malfunction

Dr.
eyelid opening apraxia ... bobvarkey #eyelid #apraxia ... #clinical #video ... #neurology #physicalexam ... #ocular
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... skin injury) • Neurologic ... spondyloarthritis • Ocular ... Leukemia, Lymphoma Ocular ... diagnosis #management #signs