36 results
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic Fever ... • Arthralgia ... Pancarditis and valvular ... RheumaticFever #pathophysiology ... #diagnosis #signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Deposition - Arthralgia ... trabecular thinning -> Avascular ... Myopathy (Also caused ... Complications #pathophysiology ... #signs #symptoms
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
pharyngeal erythema, fever ... pharyngeal erythema, fever ... endotoxin induces vascular ... skin lesions -> Vesicular ... peds #pediatrics #pathophysiology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Pathophysiology ... Ill-appearing, vital sign ... instability - New-onset fever ... Color #Targetoid #Algorithm
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... • Low-grade fever ... Back pain • Arthralgia ... Reduced libido • Signs
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Causes of Dizziness ... Differential Diagnosis Algorithm ... neurologic symptoms/signs ... Glomus Tumors - Vascular ... Differential #Diagnosis #Algorithm
Shock Classification Types - Pathophysiology Comparison

Obstructive Shock:
 • Obstructive shock is characterized by a blockage in
Classification Types - Pathophysiology ... in blood flow caused ... Depends on the cause ... cardiomyopathy. advanced valvular ... #Shock #Types #Pathophysiology
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... within morulae Signs ... after bite • Fever ... is rare (< 10% cases ... ), cough (30% cases
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... arrhythmia • Valvular ... Overproduction #diagnosis #signs ... endocrinology #pathophysiology
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
Pathogenesis of Rheumatic Fever ... Pathogenesis of rheumatic fever ... expression of vascular ... antibodies which can cause ... #Pathophysiology