56 results
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic Fever ... • Arthralgia ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Deposition - Arthralgia ... trabecular thinning -> Avascular ... Myopathy (Also caused ... Complications #pathophysiology ... #signs #symptoms
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
and signs. ... Symptoms: Tiredness ... coarse skin, Arthralgia ... Carpal timel syndrome ... Myotonia, Muscular
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Manifestations of Serotonin Syndrome ... : Tachycardia, Fever ... Clonus (inducible), Muscular ... #Symptoms #spectrum ... #signs #diagnosis
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
endotoxin induces vascular ... hemorrhagic rash; symptoms ... skin lesions -> Vesicular ... non-specific viral symptoms ... peds #pediatrics #pathophysiology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... Tuberculosis: can cause ... • Low-grade fever ... Back pain • Arthralgia
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Causes of Dizziness ... Differential Diagnosis Algorithm ... vomiting, auditory symptoms ... /signs, bidirectional ... Glomus Tumors - Vascular
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Carpal Tunnel Syndrome ... arrhythmia • Valvular ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
• Serotonin Syndrome ... Dizziness - Nausea ... Serotonin #Inhibitors #Pathophysiology ... Psychiatry #Diagnosis #Signs ... #Symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... / Symptoms / Complications ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms