28 results
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic Fever ... inflammation • Fever ... • Arthralgia ... Pancarditis and valvular ... pathophysiology #diagnosis #signs
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
– symptoms and signs ... coarse skin, Arthralgia ... , Deafness Signs ... Myotonia, Muscular ... Symptoms #Diagnosis #PhysicalExam
The Febrile Child - some diagnostic clues to evaluating the febrile child.

#Febrile #Fever #Evaluation #Assessment #Signs
some diagnostic clues ... #Febrile #Fever ... Evaluation #Assessment #Signs ... #Symptoms #PhysicalExam
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Deposition - Arthralgia ... trabecular thinning -> Avascular ... Myopathy (Also caused ... pathophysiology #signs
Pemberton's Sign caused by a Retrosternal Thyroid Goiter

Elevating the arms causes the previously flat neck veins
Pemberton's Sign ... caused by a Retrosternal ... #Pembertons #Sign ... Thyroid #Goiter #PhysicalExam ... clinical #video #vascular
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Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
platelet disorders, vascular ... Etiology: • Vascular ... Disruptions in vascular ... mountain spotted fever ... #rheumatology #
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... , Arthralgia/arthritis ... abnormalities • Muscular ... management #treatment #rheumatology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... • Low-grade fever ... Back pain • Arthralgia ... Reduced libido • Signs
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... : - Arthralgia ... Cryoglobulins Cause ... Vascular Sludging ... classification #rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
- Fever spikes ... • Arthritis, arthralgias ... Arthralgias or arthritis ... A nonpruritic macular ... AOSD #diagnosis #rheumatology