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anemia blood classification hemolytic intravascular reactions coagulation cryofibrinogenemia dic disseminated eosinophilia eosinophils extravascular hodgkins hypereosinophilia lymphoma mds myelodysplasia nonpalpable purpura
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... iron deficiency, hemolysis ... vera (PV) • Myelodysplastic ... #Diagnosis #Causes ... #hematology #secondary
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... uremic syndrome (HUS ... #differential # ... diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic ... #Diagnosis #hematology ... #rheumatology # ... #dermatology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... • MAHA: TTP, HUS ... prosthetic valve • Transfusion ... #Diagnosis #causes ... classification #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Causes purpura & ... Occurs between 0-6 hrs ... diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... Occurs between 0-6 hrs ... #Transfusion #diagnosis ... #management #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
) - Diagnosis and ... Management Definition ... blood eosinophilia Secondary ... Causes: - Allergic ... #hematology #differential
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
of fibrin split products ... extremities • Arthralgias ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... DDX: Rule Out Secondary ... blood count with differential ... #Syndromes #diagnosis ... #hematology #oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Purpura • Palpable ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
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