12 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Distributive: Sepsis ... • Cardiogenic: Acute ... MI, Acute Heart ... inopressors #diagnosis #management ... #comparison #table
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... heart failure, acute ... #Differential # ... Diagnosis #table ... #comparison #criticalcare
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... Angiotensin - "Ang II" - Sepsis ... Vasopressors #Inotropes #management ... criticalcare #summary #comparison ... #table #pharmacology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
DIC - Septic shock ... catastrophes, Acute ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Hepatic Artery: Shock ... • Infectious: Sepsis ... Liver #Injury #Differential ... #algorithm #hepatology
Non-ACS Myocardial Injury - Elevated Troponin Differential Diagnosis and Workup Algorithm

 • Chronic Myocardial Injury: End
Elevated Troponin Differential ... Pre-Coronarv): Shock ... Distribution: Acute ... Post-Coronary) • Acute ... Occlusion • Stable
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Rare: DAH, acute ... initiation • Differential ... Diagnosis: Infection (sepsis ... APML #diagnosis #management ... #hematology #oncology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
history of trauma, sepsis ... malignancy (Especially acute ... dysfunction (16%) • Shock ... causes #treatment #management ... #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
/Shock, Autoimmune ... Neurological symptoms: Acute ... Reversible course Differential ... syndrome, ADEM, Acute ... Syndrome #diagnosis #management
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
the setting of acute ... , Shock, Hypoxia ... are typically able ... physiological response to acute ... #diagnosis #management