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diagnosis hematology causes blood extravascular hemolytic management product algorithm classification dermatology nonpalpable palpable rheumatology thromboticthrombocytopenicpurpura transfusion transfusions ttp workup
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... thrombocytopenic purpura ... uremic syndrome (HUS ... #Hemolytic #Intravascular ... #Causes #differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... anemia • ... MAHA (TTP, DIC, HUS ... Differential #Diagnosis ... Algorithm #Causes #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... IVIG infusion Intravascular ... • MAHA: TTP, HUS ... • Transfusion reactions ... #Anemia #Differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic ... anemia - Splenomegaly ... : • DIC, TTP/HUS ... fever • Drug reactions
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... - MAHA: TTP, HUS ... AIHA, Transfusion reactions ... Defects: Sickle cell anemia ... Diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Thrombocytopenic Purpura ... result in severe anemia ... reflection of intravascular ... anemia Indirect ... WBC count and differential
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Post Transfusion Purpura ... Causes purpura & ... Occurs between 0-6 hrs ... Can lead to sepsis ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Post Transfusion Purpura ... Causes purpura & ... Occurs between 0-6 hrs ... Can lead to sepsis ... diagnosis #management #hematology
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