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diagnosis hematology causes management algorithm anemia blood classification hemolytic intravascular reactions bilirubinemia hodgkins jaundice lymphoma oncology thromboticthrombocytopenicpurpura transfusion transfusions ttp
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Hemolysis - Differential ... MAHA (TTP, DIC, HUS ... Differential #Diagnosis ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
uremic syndrome (HUS ... #Hemolytic #Intravascular ... #Extravascular ... #Causes #differential ... #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... IVIG infusion Intravascular ... • MAHA: TTP, HUS ... classification #hematology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Production • Hemolysis ... Hepatic Uptake • Sepsis ... Post-Hepatic - Usually has ... Algorithm #Causes #Hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Fibrin degradation products ... reflection of intravascular ... hemolysis Platelet ... WBC count and differential ... Diagnosis #Workup #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Special Blood Product ... Occurs between 0-6 hrs ... Can lead to sepsis ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Occurs between 0-6 hrs ... Blood products contain ... of transfused products ... Can lead to sepsis ... diagnosis #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
persons • It has ... nodosum • Immune hemolytic ... genes and gene products ... Immunohistochemical studies (to differentiate ... classification #hematology
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