11 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... : • Thrombotic ... syndrome (ST-HUS ... known as atypical HUS ... #diagnosis #hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... Diagnosis Table ... HUS (aHUS) ... Microangiopathy #TMA #hematology ... #differential #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
syndrome - Thrombotic ... microangiopathy: Thrombotic ... uremic syndrome (HUS ... Extravascular #Causes #differential ... #diagnosis #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... - TTP VS HUS ... Often hard to differentiate ... Comparison #Diagnosis #Table ... #Hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombotic thrombocytopenic ... purpura/hemolytic ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Production • Hemolysis ... Hepatic Uptake • Sepsis ... Post-Hepatic - Usually has ... Algorithm #Causes #Hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for Thrombotic ... Fibrin degradation products ... hemorrhage and hemolysis ... WBC count and differential ... Diagnosis #Workup #Hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Special Blood Product ... Occurs between 0-6 hrs ... Can lead to sepsis ... diagnosis #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Occurs between 0-6 hrs ... Blood products contain ... of transfused products ... Can lead to sepsis ... diagnosis #management #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
of fibrin split products ... • Fibrin split products ... necrosis) - Thrombosis ... (Thrombotic vasculopathy ... Cryoglobulinemia • TTP, HUS