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diagnosis hematology sle erythematosus oncology syndrome systemic treatment anesthesia anesthesiology causes checklist druginduced neurology activation anemia apml approach arthritis behcet
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... , oral ulcers, Lupus ... • Immunologic Workup ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Seizure disorders, Aseptic ... Diagnosis of Lupus ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... , CLL, lymphoma, ... Extravascular #Causes #differential ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... , APLA, PAC • Aseptic ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... brucellosis) • Sepsis ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Evans • ITP • Cl-NH ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
anaesthesia • Sepsis ... #Hyperthermia #Differential ... Checklist #Diagnosis #Management ... #Workup
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
initiation • Differential ... Diagnosis: Infection (sepsis ... APML #diagnosis #management ... #hematology #oncology
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