22 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... Phosphorus CLL ... ) CLL Symptoms: ... mosquito bites CLL ... transformation of the CLL
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... CLL Epidemiology ... phenomenon CLL ... • Neutropenia, anemia ... Leukemia #diagnosis #workup
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... Blood #Disorders #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Megakaryopoiesis • Aplastic Anemia ... ITP • SLE • CLL ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... malignancies • Anemia ... hemorrhage) • Chronic ... Myelodysplastic syndrome ... myeloid leukemia (CML
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... hemolysis, deficiency anemia ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... ) (e.g. lupus, CLL ... Extravascular #Causes #differential ... #anemia
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Sepsis (→ 3 ... #Hyperthermia #Differential ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... 5) Symptoms of anemia ... uw_IMresidency #CLL ... hemeonc #diagnosis #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... lymphoid malignancy (CLL ... malignancies -> CLL ... younger pts) Differential ... significance (MGUS), CLL