7 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... splenomegaly • Hepatic ... Disease #diagnosis #management ... #treatment #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
history of trauma, sepsis ... DIC • Severe Liver ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
Enlarged Spleen L - Liver ... Toxin (Drug or Heparin-induced ... ) S - Sepsis ... Thrombocytopenia #Differential ... #Diagnosis #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
brucellosis) • Sepsis ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... Renal Failure Treatment ... APML #diagnosis #management ... #hematology #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
brainstem lesions, aseptic ... Behcet disease) Differential ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Neurosarcoidosis - Diagnosis and Treatment
 • 5 to 40% of sarcoidosis, Heterogeneous, often inaugural
 • Central
Diagnosis and Treatment ... System (85%): Aseptic ... , Exclusion of Differential ... #management #neurology ... #rheumatology