15 results
Systemic Inflammatory Response Syndrome (SIRS)
•	Non-specific (infections vs non-infectious)
•	≥2 of the following:
o	Temp >38°C or <36°C
o	HR >90 bpm
o	RR
Systemic Inflammatory ... Response Syndrome ... vs non-infectious ... >2 mmol/L Management ... control (drain abscesses
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Culture Negative Abscess ... - Differential ... prior antibiotics as ... Auto-Inflammatory ... : SAPHO syndrome
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... arthritis - (Reiter’s syndrome ... ) Aseptic, within ... 1 month of infection ... psoriasis (7-30%) • Inflammatory
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
background of a highly inflammatory ... release of pro-inflammatory ... SLE], AOSD) • Infection ... brucellosis) • Sepsis ... #Diagnosis #Management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
proximal weakness, arms ... life-threatening Differential ... precipitated by: Drugs, infection ... immunosuppressants - Meds ... Gravis #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
/Sepsis/Shock, Autoimmune ... edema visualized as ... Reversible course Differential ... Diagnosis: • Infection ... #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Overview Focal inflammatory ... extensors of the arms ... Post Vaccine • Inflammatory ... Myelitis #diagnosis #management ... #neurology #differential
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
extraction • Inflammatory ... : infectious (sepsis ... anaphylaxis, toxins/meds ... Classification #diagnosis #management ... #criticalcare #differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... initiation • Differential ... Diagnosis: Infection ... (sepsis), PE, DAH ... APML #diagnosis #management
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
extraction • Inflammatory ... : infectious (sepsis ... anaphylaxis, toxins/meds ... Classification #diagnosis #management ... #criticalcare #differential