11 results
Systemic Inflammatory Response Syndrome (SIRS)
•	Non-specific (infections vs non-infectious)
•	≥2 of the following:
o	Temp >38°C or <36°C
o	HR >90 bpm
o	RR
Inflammatory Response Syndrome ... Septic Shock • ... >2 mmol/L Management ... recognition & treatment ... control (drain abscesses
Causes of Depressed / Lethargic Newborn - Differential Diagnosis Algorithm
Maternal Related:
 • Drugs (Ex. SSRI)
 •
Malformation • TORCH Infection ... Respiratory Distress Syndrome ... Aspiration • Sepsis ... • Anemia • Shock ... Algorithm #Causes #Peds
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Distributive: Sepsis ... Abdominal compartment syndrome ... Treatment Goals ... #management
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Inflammatory: infectious ... (sepsis) or not ... anaphylaxis, toxins/meds ... Classification #diagnosis #management ... #criticalcare #differential
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Inflammatory: infectious ... (sepsis) or not ... anaphylaxis, toxins/meds ... Classification #diagnosis #management ... #criticalcare #differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
/Sepsis/Shock, Autoimmune ... Reversible course Differential ... Diagnosis: • Infection ... epilepticus Treatment ... #diagnosis #management
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
Assess for high ... Pulse deficit/differential ... deficit • Shock ... Treatment - ED ... Dissection #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... life-threatening Differential ... precipitated by: Drugs, infection ... immunosuppressants - Meds ... Gravis #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... initiation • Differential ... Diagnosis: Infection ... (sepsis), PE, DAH ... APML #diagnosis #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... ->treatments include ... assessment - assess ... before beginning treatment ... - Compartment syndrome