17 results
diagnosis injury transaminitis causes acute alcoholic chronic elevated gastroenterology treatment abnormal aclf aflp chemistry cirrhosis drug druginduced failure fatty function
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... (>1000): • DILI ... #Differential # ... Diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... Hepatocellular: Viral infections ... • Autoimmune hepatitis ... #Diagnosis #Algorithm ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Coagulation Failure Infections ... Injury (DILI) ... Viral Hepatitis ... Procedures Management ... Failure #Cirrhosis #Hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Transaminitis - Differential ... Diagnosis • Infectious ... Trauma: Shock liver ... • Iatrogenic: DILI ... Diagnosis #causes #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... 10-20x normal - Infection ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Parenchyma • Infectious ... : Sepsis, Viral ... Causes #Acute #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Diagnosis: • Infections ... : Hepatitis A/B/ ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hepatomegaly - Differential ... Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Pericarditis Infectious ... #Causes #Hepatology
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