17 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... chromosome 21) Signs / Symptoms ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology ... diagnosis #signs #symptoms
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
Krabbe Disease ... case of Krabbe disease ... neurotoxic • Symptoms ... failure, cerebellar ataxia ... MarkMamloukMD #Krabbe #Disease
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Demyelinating disease ... monoparesis), limb ataxia ... , gait ataxia, and ... , hemiparesis, aphasia ... opportunistic #InfectiousDiseases
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Inflammatory bowel disease ... Metabolic: Menkes disease ... Ischaemic heart disease ... Optic neuropathy, Ataxia ... #riskfactors #symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Fits, Hemiplegia, Ataxia ... pain (20%) Renal disease ... erythematosus #signs #symptoms
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
CNS: Tremors, Ataxia ... Syndrome #diagnosis #pathophysiology ... #symptoms #signs
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... Syncope • Signs/Symptoms ... electrolyte losses - Ataxia ... muscle function, Ataxia
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Sickle-cell disease ... Sickle cell disease ... The underlying pathophysiology ... ischaemia. 2) Aplasia ... Features #Signs #Symptoms
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
findings: • Symptoms ... often- Sensory ataxia ... Sarcoidosis, Behcet disease ... Cord Compression Symptoms ... response LMN Symptoms
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... defect SIGNS/SYMPTOMS ... Cramping, Weakness, Ataxia ... Signs and symptoms ... /or cerebellar symptoms